Canadian police have made progress clearing a week-long blockade by truckers and anti-lockdown demonstrators at a crucial border crossing with the US, as large trucks left the area peacefully and authorities arrested holdouts early on Sunday.

The Ambassador Bridge, the busiest border crossing in North America, was closed because of a small group of anti-vaccine mandate protesters who were joined by supporters in cars and pick-up trucks. The bridge connects Windsor, Ontario, with Detroit, Michigan.

Drew Dilkens, the mayor of Windsor, said: “[Police] have started the enforcement, they are going to continue until they finish it, the goal is to have people move out peacefully.” The Windsor police department said it made several arrests and towed vehicles on Sunday morning, according to its Twitter account and a news release.